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PYRIMIDINE DIMERS
Descriptors Found:
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DeCS
Descriptor
English
:
Pyrimidine Dimers
Descriptor
Spanish
:
Dímeros de Pirimidina
Descriptor
Portuguese
:
Dímeros de Pirimidina
Synonyms
English
:
Thymine Dimers
Tree Number:
D03.383.742.686.600
D13.695.578.424.600
D13.695.740.600
Definition
English
:
Dimers found in
DNA
chains damaged by
ULTRAVIOLET RAYS
. They consist of two adjacent
PYRIMIDINE NUCLEOTIDES
, usually
THYMINE nucleotides
, in which the pyrimidine residues are covalently joined by a cyclobutane ring. These dimers block
DNA REPLICATION.
See Related
English
:
DNA Damage
History Note
English
:
77
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
12177
Unique Identifier:
D011740
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS